Tips for uniportal video assisted thoracic surgery S1 segmentectomy
Surgical Technique

Tips for uniportal video assisted thoracic surgery S1 segmentectomy

Luciano Bulgarelli Maqueda1,2, Lei Jiang1

1Thoracic Surgery Department, Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China; 2Cardiothoracic Surgery Department, Hospital Córdoba, Universidad Nacional de Córdoba, Córdoba, Argentina

Correspondence to: Lei Jiang. Thoracic Surgery Department, Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China. Email: jiangleiem@aliyun.com.

Abstract: With the advent of lung cancer screening programs, the role of segmentectomy is gaining interest. The evolution of the technique has achieved minimally invasive approaches such as uniportal video assisted thoracic surgery (UniVATS) while preserving its oncological principles. Key steps of the technique as the intersegmental plane demarcation method are still under assessment, but none of them has achieved fully scientific validation yet. We describe our technique for S1 segmentectomies and our currently used method for the intersegmental plane delimitation.

Keywords: Video assisted thoracic surgery (VATS); technique; segmentectomy; uniportal VATS (UniVATS)


Received: 27 September 2019; Accepted: 15 January 2020; Published: 15 March 2020.

doi: 10.21037/vats.2020.01.06


Introduction

Anatomic segmentectomies are playing an important role in thoracic surgery as a result of the increased implementation of screening programs for lung cancer which have lead surgeons to face lesions in earlier stages more often (1,2). Segmentectomy has become an option for the management of small lesions allowing anatomical pulmonary resections to be used both for diagnosis, in cases not suitable for percutaneous lung biopsy, as well as for the treatment of lesions while sparing lung parenchyma (3).

The currently accepted indication are ground glass opacity (GGO) lesions with a diameter lesser than 2 cm in a peripheral location in context of lung cancer suspected diagnosis (cT1aN0M0) for selected patients (4), benign lesions, and pulmonary metastases.

The technique has evolved from open thoracotomy, to a hybrid VATS technique adapted by Nomori et al. (5), later, Rocco et al. implemented it through VATS (6), and lately Gonzalez-Rivas et al. developed the UniVATS approach (7). Our group started its UniVATS practice in 2014; afterwards this paper’s author contributed to Xie et al. in the largest series of segmentectomies by UniVATS approach published in 2016 (8).

Regarding the technique itself, a complete resection of the affected segment is essential while treating lung cancer because it could have an impact in the long-term results. During its evolution, the open technique’s steps were adapted to keep its oncological principles. Different possible solutions came up for this objective, as the way of dissecting segmental structures or intersegmental margin delimitation and division. We detail our approach and technique for UniVATS S1 segmentectomies.


Patient selection

The patient selection shares indications and contraindications for every UniVATS procedure. It also shares the indications already mentioned for segmentectomies such as less than 2 cm GGO lesions (T1a N0 M0). In the context of lung cancer patients, it is important to rule out N2 disease or calcified lymph nodes before the operation.


Preoperative preparation

The patient’s management is approach in a “fast-track” strategy since the preoperative preparation using an enhanced recovery after surgery (ERAS) protocol. This could have an impact on the patient’s recovery by minimizing the stress response to surgery, with a possible repercussion on the outcomes, length of stay, and costs (9,10).

We use percutaneous localization of the lesions when suitable. A hook-wire is placed in the lesion before the operation.


Equipment and set up

Patient’s position

The patient is routinely managed under general anesthesia with one-lung ventilation, although in selected cases we choose a non-intubated anesthesia approach.

The patient is positioned in a lateral decubitus position according to the side of the lesion to be operated. When using the subxiphoid approach, a 45 degrees intermediate lateral decubitus is chosen.

Set up

A secondary instruments table is placed over the operating table at the patient’s feet. The scrub nurse and the main instruments table are located at the right side of the operating table beside the secondary instruments table. The surgeon will place himself in front of the patient and the assistant will be positioned at the patient’s back, beside the scrub nurse.

The screen, camera and light source are placed at the head of the operating table. The use of a FullHD or UltraHD camera is important as it allows clearer distinction of structures to be dissected or transected. The endoscope used is a 30 degrees, 10 mm thoracoscope.

A set of UniVATS double jointed instruments is used. In case we use the subxiphoid approach, a subxiphoid UniVATS instruments set is essential because they are longer and they have a different angled curve than those designed only for UniVATS intercostal approach. This way the surgeon is able to reach any intra-thoracic structure and aspect. We also use advanced energy devices for dissection and vessel division.

Surgical technique for UniVATS S1 segmentectomy

UniVATS approach

An incision smaller than 4 cm is placed between the middle and anterior axillary line on the 5th intercostal space. For the right upper lobe approach, the 4th intercostal space is suggested. Some surgeons prefer the 4th intercostal space also for upper lobes segmentectomies.

The Serratus anterior muscle fibers should be opened without cutting them in a muscle-sparing way.

The intercostal muscles should be divided along the upper edge of the inferior rib, trying not to divide it more than necessary to decrease the trauma to the intercostal space. After entering the pleural cavity, a wound retractor is placed.

Subxiphoid UniVATS approach

A 3 to 4 cm incision is performed in a longitudinal median plane from the xipho-sternal junction to 1cm below the xiphoid process. We resect the process and then we use a combination of blunt and energy retrosternal dissection towards the hemithorax to be approached until entering the pleural cavity. A part of the mediastinal fat pad is resected and a wound retractor is placed.


S1 segmentectomy technique

It is essential to meticulously review the patient’s anatomy by all the available means to be sure the lesion’s location, identification of anatomical structures, and to define the strategy. In the following description, anatomical structures are named by nomenclature previously described by Nomori et al. (11).

The Lung is retracted posteriorly and slightly inferiorly by using a lung grasper, this traction will expose the superior pulmonary vein in the hilum. We dissect the hilum using hook, cautery or energy devices from the ventral aspect to a dorsal direction identifying the different hilar structures. The segment structures are identified and then carefully dissected with a combination of blunt and energy dissection, this step will make the procedure safer and faster. To divide the vessels we prefer to tide their proximal portion using a 3.0 silk suture, and later we divide the distal portion by an advanced energy devices (Figure 1). This way we deal firstly with the V1 vein and then we approach the A1 artery (Figure 2).

Figure 1 Image showing a right segment 1 artery (A1), already dissected and then tied proximally, being transected distally by an advanced energy device, during a right S1 subxiphoid UniVATS segmentectomy. UniVATS, uniportal video assisted thoracic surgery.
Figure 2 Video demonstrating the dissection steps during a right S1 subxiphoid UniVATS segmentectomy (12). UniVATS, uniportal video assisted thoracic surgery. Available online: http://www.asvide.com/watch/33094

After dividing the vessels, the bronchus is dissected and tied proximally and then is partially cut open distally by scissors. Afterwards, a central vein catheter is inserted into the distal segmental bronchus and air is insufflated defining the intersegmental plane (Figure 3), in a technique reported previously by the author (13) which we detail further in this paper. Thereafter, the bronchus is divided by stapler, the distal bronchial stump is lifted and dissection is performed by cautery along the bronchus, dividing part of the intersegmental plane and some branches of the affected segment’s drainage vein, with no special dissection for intersegmenal veins (Figure 4). This dissection will leave a space to be used later for the stapler positioning while dividing the rest of the intersegmental plane, potentially achieving its more accurate division by helping to compress less lung parenchyma belonging to neighboring segments in the stapling line, also promoting a better future insufflation of the remaining segments.

Figure 3 Picture presenting the B1 bronchus, already tied proximally and divided distally to the tie, with the central line catheter about to be inserted in its lumen.
Figure 4 Image showing the B1 bronchus lifted by a grasping forceps and the dissection about to start by cautery.

Once the procedure is concluded, we check for air leakage, hemostasis and a 28 Fr chest drain is placed at the posterior part of the incision.

Right S1 segmentectomy highlights

After identifying V1 and the central vein, we dissect the structure and we transect it. By dividing V1 better access is achieved for dissecting A1. At this point the recurrent A2 must be identified and preserved, A1 runs towards the B1 bronchus, contrary to a recurrent A2 that goes apart from it. Then if A2 is not clearly identified, the first dorsal branch from A1 must be preserved because it might be the recurrent A2 (11). Afterwards the B1 is identified, exposed and divided after the delimitation of the segment (Figure 2). Finally the intersegmental borders are divided by staplers.

Left S1 segmentectomy highlights

Anatomical differences determine the S1+2 segment in the left lung. Anyway, the left S1 portion can be resected separately when the anatomy is clear by an atypical segmentectomy. After dissecting V1+2 a, a superior branch of A1+2 (A1+2 a+b) can be identified and divided. Afterwards, the identification and dissection of B1+2 a+b is possible (Figure 5). We repeat the process before detailed for the segmentectomy completion.

Figure 5 Video demonstrating the dissection steps during a left S1 subxiphoid UniVATS segmentectomy (14). UniVATS, uniportal video assisted thoracic surgery. Available online: http://www.asvide.com/watch/33095

Postoperative management

Normally, the patients are extubated in the OR and transferred to a post anesthesia care unit (PACU) where they will be monitored for a short period of time of at maximum 2 hours. After that period the patients will be transferred to the regular ward or the ICU, according to the specific criteria.

If the patients remain stable during their stay at the ward, the first X-ray will be done during the next morning. The pain management protocol includes patient control analgesia (PCA) and oral analgesics if needed.

Indications for removing the chest tube, are the same as in the open thoracotomy technique.

The attachment to the ERAS strategy including early mobilization, effective analgesia, pulmonary rehabilitation and appropriate drain management could be helpful (9,10).


Tips tricks and pitfalls

Tide instead of clip

We choose tying rather than using anti-slip clips for small vessels, because the use of clips would result in a “mined-field”, creating obstruction for subsequent complex maneuvers such as stapling or those needed to divide the intersegmental plane. After tying the proximal portion of the vessel, we use an advanced energy device to transect it distally to the tie (Figure 1).

Lifted bronchus dissection

As in the classic open technique, we lift the distal bronchial stump and dissect the parenchyma in its posterior aspect (Figure 4). We avoid dissecting the intersegmental veins distally, which is time consuming and difficult. By dividing part of the intersegmental plane we gain space for maneuvering thus decreasing the risk of damaging surrounding structures (Figure 6); Additionally this technique creates a space to put the anvil of the stapler while dividing the delimited intersegmental border after one of the insufflation techniques; This will provide a more anatomical resection, with a possible impact on the long-term results and on the remaining lung’s functionality.

Figure 6 Video playing the dissection of part of the intersegmental plane, performed after the distal bronchial stump is lifted, during a right S1 UniVATS segmentectomy (15). UniVATS, uniportal video assisted thoracic surgery. Available online: http://www.asvide.com/watch/33096

Open insufflation technique

Currently we lack an efficient method to demarcate the segments to be removed. Our technique is based on the selective insufflation of the excluded segment in a safe, less time consuming and well-balanced cost-effective way. The elements needed for this method are a central venous catheter connected to a 60 mL Luer-slip syringe.

Once the bronchus is exposed, a 3.0 silk suture tie is placed at its proximal portion. Next, the bronchus is partially cut distally to the tie in its anterior aspect. This will allow the tip of the central vein catheter to be inserted into its lumen (Figure 3). Following this, air is blown from the syringe insufflating the affected segment until the demarcation intersegmental line is noticed (Figure 7).

Figure 7 Video presenting the open insufflation technique during a S3 subxiphoid UniVATS segmentectomy (16). UniVATS, uniportal video assisted thoracic surgery. Available online: http://www.asvide.com/watch/33097

With this method we notice advantages such as a better demarcation line than in the inflation-deflation technique, possibly due to less collateral inflation taking place, potentially achieving more accurate margin’s resection. Another advantage is the time invested in this procedure, avoiding waiting 15 minutes for the lung to deflate. Furthermore, no special or expensive equipment is needed (bronchoscope, high-frequency oscillation device, or near-infrared imaging systems); Also these procedure’s specific complications are avoided. It is a feasible, and we believe more effective method to approach this step.

A possible pitfall could be that the partial cut in the segmental bronchus and the insertion of the catheter could be difficult for inexperienced surgeons.


Conclusions

Segmentectomies are playing a growing role in thoracic surgery. Along the evolution of their technique, efforts have been invested in order to achieve a less invasive technique while respecting the oncological principles. We believe that our approach achieves these goals in a more efficient way. We still must fulfill the scientific scrutiny that could demonstrate its benefits compared to other techniques and to assess its long-term results.


Acknowledgments

None.


Footnote

Conflicts of Interest: The authors have no conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Written informed consent was obtained from the patient for publication of this manuscript and any accompanying images.


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  12. Bulgarelli Maqueda L, Jiang L. Video demonstrating the dissection steps during a right S1 subxiphoid UniVATS segmentectomy. Asvide 2020;7:054. Available online: http://www.asvide.com/watch/33094
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  14. Bulgarelli Maqueda L, Jiang L. Video demonstrating the dissection steps during a left S1 subxiphoid UniVATS segmentectomy. Asvide 2020;7:055. Available online: http://www.asvide.com/watch/33095
  15. Bulgarelli Maqueda L, Jiang L. Video playing the dissection of part of the intersegmental plane, performed after the distal bronchial stump is lifted, during a right S1 UniVATS segmentectomy. Asvide 2020;7:056. Available online: http://www.asvide.com/watch/33096
  16. Bulgarelli Maqueda L, Jiang L. Video presenting the open insufflation technique during a S3 subxiphoid UniVATS segmentectomy. Asvide 2020;7:057. Available online: http://www.asvide.com/watch/33097
doi: 10.21037/vats.2020.01.06
Cite this article as: Bulgarelli Maqueda L, Jiang L. Tips for uniportal video assisted thoracic surgery S1 segmentectomy. Video-assist Thorac Surg 2020;5:8.