Article Abstract

Vein-first vs. artery-first: “does the order of vessel ligation during pulmonary lobectomy for NSLC affect circulating tumor cells and patient survival?”

Authors: Benjamin Wei, Alex Abdullayev


In the May 2019 issue of JAMA Surgery, Wei and colleagues report the results of a fascinating two part study: the first consists of a multicenter, randomized clinical trial evaluating whether ligating effluent veins first during thoracoscopic lobectomy can reduce the dissemination of tumor cells in patients with non-small cell lung cancer (clinical stage I–II) (1); the second comprises a propensity-matched retrospective analysis of overall survival (OS) and disease-free survival (DFS) in patients undergoing vein-first versus artery-first lobectomies.